CreationNation

Few things I do on mine that have helped me:

1) Make sure you have email verification turned on, as well as Captcha (even though it isn't full proof).

2) Set your forum to notify you via email when someone joins. This has aided me in weeding out spammers very quick since I am working here all day at my email. you can detect a spammer 80% of the time once you get used to seeing the trends (user name structure, @emaildomains.com, etc.).

3) Before you completely delete/ban/prune a spammer, see what email address they used. If it is something like joeblow@buygreatdrugs.info then, add buygreatdrugs.info to your admincp>user banning options>banned email list. Do this every time otherwise you will contonue to allow those spammers/bots to use that email domain. Here is a starter list for you if you like:
4) Add disallowed keywords to your admincp>registration options>illegal user names list. I added a bunch that were very recurring by spammers such as:
Those measures have helped me DRASTICALLY over the last few months. I get the occasional ipod pusher and such but not so much the drug spammers etc. any more.

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Deron
www.creationnation.com
www.ultimatemetal.com
www.metalages.com