Well, you gotta be careful, cause a rush of affiliates can cause more harm to your brand in the long run. When you select affiliates, make sure to properly vet them so you know they aren't pulling crazy stunts with your brand, company, or product. Listing your program might get your more noticed quickly, but it might not be the best quality if you get my drift.
A good approach is to look for people in your niche/industry that have sites with good traffic and get them to be an affiliate for you. Work with them closely, make them good money, and word will start spreading about your program, product, etc. Make sure to split test your product/service, and always have new marketing material.
I launched a product several months back, and have noticed that affiliates want converting landers more than anything. So my main goal for the next several months is to split test landers, elements on them, always looking to increase conversions. But I also know that different traffic sources exhibit different responses. So by communicating that with my affiliates, we're all able to make more money together.
Realistically if I had 10,000 affiliates like Norb/NCmedia does for his Dubturbo product, there is no way I can give individual attention. The 80 / 20 rule applies - well really 95 / 5 - where 5% of the affiliates are going to drive in 95% of your affiliate program's revenue. Concentrate on the ones that make you the most money

- Or you'll dilute yourself with one-off affiliates.
Being on the owner side is crazy, It's a hard game to play. There are better people like NCMedia is better suited to ask and answer questions about affiliates. Or Mont, but he's my secret...