I used it back in the day when it was still owned by Macromedia. I'm sure the pros know, but I can't really see much of a difference between Fireworks, Photoshop and Imageready.
Fireworks is my design program of choice. I've used it exclusively since FW 3 and as the only graphics I do are for teh interwebz it's built for people like me. I don't edit photos and I've never actually used PS. If I do mess around with photos I use Pixelmator.