Ok I had to reply to this. This is probably one of the most non-sensical things I have heard in awhile.
Here we go...
When I (and most of us) think of connection, I usually think of AT LEAST two things coming together to make that connection.
Ok, so let's define one connection as something that brings at least 2 pieces of matter (whatever matter may be) together to make a connection. You obviously cannot make a connection with one piece of matter as we have defined it above, so you need at least two pieces.
Oh yea, just to be accurate, let's define
matter as anything that takes up mass or volume.
Based on this, lets say you had "x" connections in your brain. You would then automatically need "2x" pieces of matter to do this. Therefore, the minimum amount of matter in the universe has to be at least two times as the number of connections in one brain.
I have no idea how that statement can be considered valid in any conceivable way. Unless of course your idea of a connection was different then what we defined above (in other words, you're saying you could make a connection with one particle or less).
Also remember, one synapse is probably made of many pieces of matter.