Thanks for all the suggestions everyone... I decided to try a little of each recommended in the thread.
Grabbed a bean bag wrist support, changed ergos as recommended (removed chair arms, raised height, tilted forward), ditched the mouse pad, increased tracking (holy christ btw!), and an Evoluent is on the way. Still looking at changing my desk (lots of choices out there).
It's been about 4 days now since the changes and the pain is much more manageable. Still some tension and sporadic pain, but I'd imagine it won't go away all at once.
Also added pull ups to my routine periodically throughout the day, and change mouse positions every once in a while... DEFINITELY helps stretch out the forearm/arm muscles and ease the tension just by hanging from a pull up bar.